In March and April, we reported on the continued buildout of AI infrastructure, pharmaceutical capacity, and defense production across the United States. In May, that momentum not only held but deepened, with several of the country's most consequential industrial announcements of the year arriving in a single month. Life sciences dominated investments, with a pharmaceutical giant opening its first dedicated genetic medicine facility, a nuclear innovator breaking ground on the world's largest actinium-225 plant, and a stem cell pioneer opening a new iPSC headquarters, all in the span of weeks.
And in another major development, quantum computing crossed a threshold in May, with the United States announcing its first purpose-built quantum chip foundry. Defense manufacturing continued to expand, and major announcements in materials and recycling pointed to a broader reshoring of critical industrial supply chains.
Spanning more than ten states and and representing tens of billions in investment, here are the latest new plants and expansions announced across the U.S. in May 2026.
Advanced Technology And Semiconductor Manufacturing
Anderon -- IBM And The Department Of Commerce Announce America's First Quantum Chip Foundry In New York
IBM and the U.S. Department of Commerce announced on May 21 a Letter of Intent to establish Anderon, a new standalone quantum wafer foundry to be headquartered in Albany, New York, and the nation's first purpose-built quantum chip foundry. The project is backed by a proposed $1 billion in CHIPS and Science Act incentives from the Department of Commerce, matched by $1 billion in cash from IBM, with additional intellectual property, workforce, and assets contributed by IBM. Anderon will operate as a 300-millimeter quantum wafer foundry, initially focused on wafer fabrication for superconducting qubit technology and supporting electronics, with plans to expand into other quantum modalities over time.
Arvind Krishna, Chairman and CEO of IBM, said, "IBM has pioneered quantum computing for decades. Our work in silicon wafer fabrication has been a key to IBM's success and will be critical to enable a broader quantum technology landscape that will reshape global innovation and economic competitiveness. With the support of the U.S. Department of Commerce, Anderon will be well-positioned to fuel America's fast-growing quantum technology industry."
Aerospace And Defense Manufacturing
Lockheed Martin Breaks Ground On THAAD Munitions Production Center In Alabama
Lockheed Martin broke ground on May 21 on a new Munitions Production Center in Troy, Alabama, as part of its broader commitment to invest more than $9 billion through 2030 to scale U.S. munitions production. Building 47 will add 87,000 square feet of production space to the Troy site, nearly doubling its existing manufacturing footprint, and will support production of Terminal High Altitude Area Defense interceptors and future work tied to the Next Generation Interceptor program. The expansion is expected to create a significant number of new jobs over the next three years, adding to Lockheed Martin's approximately 4,000 employees in Alabama.
Jim Taiclet, Chairman, President, and CEO of Lockheed Martin, said, "We have already invested well over a billion dollars in this expansion, which directly strengthens deterrence and helps ensure our service members and allies have the capabilities they need when they need them."
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BAE Systems Invests $135 Million In Texas And New Hampshire Defense Facilities
BAE Systems announced on May 20 a $135 million investment for facility enhancements at its campuses in Austin, Texas, and Hudson, New Hampshire, funded entirely through the company's own capital. Approximately $85 million is being directed to the Hudson campus, where advanced capabilities are designed, developed, and tested, with work including the renovation and reconfiguration of roughly 65,000 square feet of workspace to improve workflow and support future requirements from U.S. and allied customers. A separate $50 million manufacturing overhaul at the Austin site will scale factory infrastructure to meet defense requirements for precision munitions.
Dave Harrold, Vice President and General Manager of Countermeasure and Electromagnetic Attack Solutions at BAE Systems, said, "This investment in capacity underscores BAE Systems' long-term commitment to equipping U.S. warfighters with the capabilities they need, when they need them. We're building for the future, delivering at speed and scale, and enabling the capabilities required to deter aggression."
Collins Aerospace Expands Radar Manufacturing In Largo, Florida
Collins Aerospace, an RTX business, announced on May 11 a $26.5 million investment to expand its Largo, Florida facility to accelerate the production of commercial aviation radars and multi-domain security solutions for defense customers. The investment will create more than 100 new highly skilled jobs across engineering and factory operations, and the new radar production area is expected to become fully operational by late 2026. The facility will support work under the FAA's Radar System Replacement Program, including production of the Condor Mk3 cooperative surveillance radar and the ASR-XM non-cooperative radar.
Nate Boelkins, President of Avionics at Collins Aerospace, said, "As global airspace becomes more congested and contested, customers need secure, interoperable systems for seamless coordination. This expansion strengthens our ability to deliver critical capabilities that keep airline passengers safe and military operators mission-ready, faster."
Life Sciences And Biomanufacturing
Lilly Opens First Dedicated Genetic Medicine Facility And Commits Additional $4.5 Billion In Indiana
Eli Lilly announced on May 6 an additional $4.5 billion investment across two of its three Lebanon, Indiana sites, while simultaneously opening Lilly Lebanon Advanced Therapies, its first dedicated genetic medicine manufacturing facility. The new investment brings the company's total Indiana capital expansion commitments since 2020 to more than $21 billion. The $4.5 billion will incorporate new process designs and technologies at Lilly Lebanon API, one of the company's future active pharmaceutical ingredient sites, as well as the newly opened Lilly Lebanon Advanced Therapies facility, which will handle both clinical and commercial production of genetic medicines. The Lebanon Advanced Therapies campus is expected to support more than 1,000 jobs.
David A. Ricks, Chair and CEO of Eli Lilly, said, "From genetic medicines that could one day prevent disease at its source, to Foundayo, a pill making weight loss treatment accessible to millions, we are not just discovering the medicines of the future -- we are building the world's most advanced plants to make them. When our Lebanon API site opens in 2027, it will be the largest API production site in U.S. history, a commitment we chose to build here, at home."
TerraPower Isotopes Breaks Ground On World's Largest Actinium-225 Manufacturing Facility In Philadelphia
TerraPower Isotopes broke ground on May 6 on its flagship Bellwether Laboratory, a 250,000-square-foot actinium-225 manufacturing facility located in Philadelphia's Bellwether District. The $450 million facility is expected to increase global actinium-225 production capacity twentyfold, supporting the development of targeted alpha therapies for cancer treatment, and is projected to create approximately 225 full-time jobs and roughly 500 construction jobs. The company selected Philadelphia following a nationwide evaluation process that reviewed more than 350 potential locations across eight metropolitan areas.
Scott Claunch, President of TerraPower Isotopes, said, "The Bellwether Laboratory is purpose-built to meet the needs of a growing industry that is working to transform how cancer is treated. With a highly trained and dedicated team, we are thrilled to be building our flagship facility right here in Philadelphia."
Novartis Breaks Ground On Radioligand Therapy Manufacturing Site In Denton, Texas
Novartis broke ground on May 7 on its new 46,000-square-foot radioligand therapy manufacturing site in Denton, Texas, the company's first manufacturing facility in Texas and its fifth RLT site nationwide. The $280 million facility, part of Novartis' broader $23 billion investment in U.S. manufacturing and research, is expected to create between 150 and 175 jobs in bioengineering, advanced manufacturing, quality, and operations. The site is expected to become fully operational in 2028 and will serve patients across the southern United States.
Vas Narasimhan, CEO of Novartis, said, "Radioligand therapy is transforming how we treat cancer, and expanded manufacturing is essential to delivering these therapies at scale. Breaking ground in Denton further strengthens our U.S. supply chain and helps ensure patients can receive these highly personalized treatments when and where they need them."
FUJIFILM Cellular Dynamics Opens New iPSC Headquarters And Manufacturing Facility In Madison, Wisconsin
FUJIFILM Cellular Dynamics celebrated the opening of its new headquarters and iPSC development and manufacturing facility in Madison, Wisconsin on May 19. The new site is expected to quadruple the company's iPSC-based research products and services manufacturing footprint and expand capabilities across its research product portfolio, including the iPSC-derived iCell product lines used in drug discovery. The facility is also designed to accommodate future contract manufacturing of cell therapy products, from investigational drug manufacturing to commercial production.
Tomoyuki Hasegawa, President and CEO of FUJIFILM Cellular Dynamics, said, "The opening of this facility is an exciting milestone for FUJIFILM Cellular Dynamics and represents a crucial next step for scaling the infrastructure needed to support the next generation of iPSC-based research and therapeutics in the U.S. By expanding our development and manufacturing capabilities, we can better support partners working to translate stem cell science into real clinical impact."
Niowave Breaks Ground On $75 Million Actinium-225 Production Facility In Lansing, Michigan
Niowave announced on May 21 the groundbreaking of a new $75 million production facility in Lansing, Michigan, its second dedicated production site in the city. The new facility will substantially increase domestic supply of actinium-225, a critical isotope used in next-generation targeted cancer therapies, and is expected to create approximately 70 highly skilled jobs in R&D, engineering, and quality assurance. The site is expected to become operational in 2028.
Mike Zamaira, Chief Executive Officer of Niowave, said, "This expansion reflects our continued commitment to advancing the future of targeted alpha therapy and investing in the Lansing community. Actinium-225 has the potential to transform cancer treatment, and this new facility significantly strengthens our ability to deliver this critical isotope so that therapies can reach patients who need them."
Building Materials, Metals, And Industrial Manufacturing
USG Corporation Invests $1.175 Billion In New Gypsum Production Facility In Orange, Texas
Governor Greg Abbott announced on May 14 that USG Corporation will invest $1.175 billion to establish a new production facility in Orange, Texas, qualifying the project under the Texas Jobs, Energy, Technology, and Innovation program. USG is making an initial investment of $650 million at the site, which will be built at a former International Paper mill, and the project is expected to create nearly 200 jobs. The facility will expand USG's presence in Texas, where the company already operates manufacturing locations in Dallas, Galena Park, and Sweetwater.
Chris Macey, CEO of USG Corporation, said, "The USG family is excited to be a part of the Orange community, and we are committed to being a trusted neighbor and employer for decades to come. This new plant builds upon our hundred-year-old roots in Texas that include manufacturing operations in Sweetwater, Dallas, and Galena Park, and reflects our continued commitment to our customers' success and the state's prosperity."
American Steel And Aluminum Opens Second Syracuse Manufacturing Facility In New York
American Steel and Aluminum opened a new 50,000-square-foot manufacturing facility in Syracuse, New York on May 5, its second location in the city. The new site adds production capacity to meet accelerating demand from customers in data center infrastructure, defense, renewable energy, and industrial manufacturing. The additional footprint enables the company to increase throughput, shorten lead times, and bring new processing capabilities closer to customers. ASA now operates more than 450,000 square feet of manufacturing and processing space across facilities in Maine, Massachusetts, New York, and New Hampshire. Sam Blatchford, President of American Steel and Aluminum, said, "This expansion is a direct response to what we're hearing from the market. Our customers in data centers, defense, and energy are scaling fast, and they need a domestic manufacturer who can scale with them. That's exactly what we're building in Syracuse."
Sortera Technologies Opens AI-Powered Aluminum Processing Facility In Lebanon, Tennessee
Sortera Technologies announced on May 21 that its new processing facility in Lebanon, Tennessee reached full operational status, effectively doubling the company's total annual processing capacity to an estimated 240 million pounds of recycled aluminum alloys. The facility uses the company's proprietary AI-driven sorting technology to transform mixed alloy scrap into high-value materials for the automotive, construction, and aerospace industries, keeping critical materials within the U.S. economy and reducing reliance on international imports. The Lebanon location positions Sortera's upcycling platform at the heart of the Battery Belt and the Southern automotive manufacturing corridor.
Michael Siemer, CEO of Sortera Technologies, said, "The performance of our Markle facility proved there is strong appetite for sustainable, high-quality recycled aluminum. By bringing our Lebanon operation online, we are meeting that demand head-on -- effectively doubling our capacity and providing a streamlined, localized supply chain for our regional customers."
Data Infrastructure Manufacturing
STULZ USA Announces 300,000-Square-Foot Cooling Solutions Facility In Denton, Texas
STULZ USA announced on May 5 plans to construct a new 300,000-square-foot manufacturing and testing facility in Denton, Texas, adjacent to its existing location. The new facility is expected to open in spring 2027 and will serve as a hub for manufacturing and testing of both air-cooled and liquid-cooled solutions designed for digital infrastructure applications, including data centers and other mission-critical environments. The project is expected to create hundreds of new jobs in the Denton region.
Brian Hatmaker, President of STULZ USA, said, "This expansion reflects our continued confidence in the North American market and our commitment to being closer to our customers. By growing our presence in Denton, we are strengthening our ability to deliver innovative, high-quality cooling solutions that meet the evolving needs of digital infrastructure across the country."
Food And Beverage Manufacturing
Coca-Cola Consolidated Invests $35 Million In New Glass Bottle Production Line In Indianapolis
Coca-Cola Consolidated announced on May 4 a $35 million investment to add a new glass bottle production line to its Indianapolis, Indiana manufacturing facility, located at 5000 W. 25th Street. Construction of the new line is anticipated to begin in late 2026, and the expansion is expected to create 15 to 20 new full-time jobs. The investment will make the Indianapolis facility one of only three locations in the nation within the Coca-Cola system that bottles beverages in glass.
Dave Katz, President and Chief Operating Officer of Coca-Cola Consolidated, said, "This expansion is another example of how we strategically invest in our business to build a solid operational foundation and create opportunities for our teammates in the communities where they live and work."
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