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In August 2025, America’s manufacturing base continued to expand across a wide range of sectors. Biotech companies announced cutting edge pharmaceutical and medical isotope plants, heavy industry invested in energy infrastructure and materials production, and consumer goods makers expanded footprints to meet demand. We saw new steel and energy infrastructure plants opening up, legacy companies announcing massive multi-state investments, and more, encompassing billions of dollars in new capital and thousands of jobs.
Let’s take a closer look at the new operations shaping the next chapter of American manufacturing.
Genentech, a member of the Roche Group, started construction on a 700,000 square foot facility in Holly Springs, North Carolina. The $700 million project will manufacture next generation metabolic medicines and is expected to add more than 400 manufacturing jobs and 1,500 construction jobs. CEO Ashley Magargee underscored the importance of the site, saying, “We are proud to break ground on our new manufacturing site in Holly Springs, North Carolina, with its world class biotech talent, top research institutions and a robust infrastructure that will enable our growth for years to come. With this step, we are taking action to deliver more life changing medicines to patients faster, contribute to the local economy, and bolster manufacturing and innovation in the U.S.” The plant is part of Roche’s broader plan to invest $50 billion in U.S. manufacturing.
Johnson & Johnson announced a $2 billion commitment to enable manufacturing at Fujifilm Diosynth Biotechnologies’ site in Holly Springs, North Carolina. The new 160,000 square foot facility will create about 120 jobs. CEO Joaquin Duato noted that the company continues to strengthen its U.S. presence: “Johnson & Johnson has more manufacturing facilities in the U.S. than in any other country, and we continue to strengthen our presence here. With the recent signing of the One Big Beautiful Bill Act, we continue to expand our investment in the U.S. to lead the next era of healthcare innovation.”
AbbVie will invest $195 million to construct a new active pharmaceutical ingredient facility at its North Chicago, Illinois campus. Construction will begin in late 2025, expanding domestic API production for neuroscience, immunology and oncology medicines.
CEO Robert A. Michael highlighted the long term commitment, saying, “Over the next decade, AbbVie will expand production of API, drug product, peptides and medical devices in the U.S. to support future medical breakthroughs. This is an important step to maintain U.S. leadership in pharmaceutical innovation and deliver next generation medicines that make a remarkable impact on patients’ lives”
Nusano, a physics company, cut the ribbon on a 190,000 square foot radioisotope production facility in West Valley City, Utah. The plant can produce more than 40 radioisotopes for cancer diagnostics, therapeutics and industrial uses. “Nusano is commercializing breakthrough technologies to enable innovation, improve human health, and power exploration,” said Chris Lowe, CEO of Nusano
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Philips announced more than $150 million in U.S. investments to expand manufacturing and research capabilities. The company will add 24,000 square feet of manufacturing space and a 40,000 square foot warehouse at its Reedsville, Pennsylvania site, creating about 120 jobs. It will also expand its image guided therapy facility in Plymouth, Minnesota, adding over 150 jobs. Jeff DiLullo, Philips’ chief region leader for North America, emphasized the company’s dual focus on innovation and jobs:
“Each year, Philips spends $900 million in R&D in the U.S. to drive innovation and deliver cutting edge technology that empowers healthcare professionals to diagnose, treat and monitor patients more effectively. Increasing our manufacturing and R&D capabilities will create jobs and accelerate our ability to deliver better care for more people with innovative AI enabled solutions”.
Hitachi Energy will invest $106 million to expand its transformer component manufacturing facility in Alamo, Tennessee. The project adds more than 60,000 square feet of manufacturing, warehouse and office space and will create about 100 jobs. Steve McKinney, head of Transformers for North America, explained the company’s motivation: “This facility plays a critical role in meeting fast-growing energy demand from AI as well as grid expansion and modernization, and we’re proud to grow our footprint and strengthen domestic manufacturing right here in Tennessee,” said Steve McKinney, Head of Transformers, North America.
Brazos Midstream is constructing the Sundance II natural gas processing plant in Martin County, Texas. The $185 million facility will process up to 300 million cubic feet per day and expand the company’s midstream infrastructure. CEO Brad Iles outlined the project’s impact:
“Brazos Midstream is excited to proceed with the construction of our new Sundance II facility, a 300 MMcf/d cryogenic gas processing facility in Martin County. Once commissioned, this addition will increase our combined Midland Basin processing capacity to 500 MMcf/d. This investment provides mission critical gas infrastructure and reliable takeaway capacity to energy producers throughout the Permian Basin, and we are grateful to Governor Abbott and local officials for their support”
The Lower Colorado River Authority (LCRA) celebrated the start of Phase One of the Timmerman Power Plant in Maxwell, Texas, which provides 380 MW of dispatchable electricity. The project will create more than 300 jobs. Governor Abbott described the importance of the project, noting that it will help ensure reliable power for Texas’ growing economy, while LCRA General Manager Phil Wilson stressed its long term benefits: "LCRA is proud to bring the first unit of the Timmerman plant online to provide additional reliable power to our growing state," said LCRA General Manager Phil Wilson. Industrial & Materials
Belgian intralogistics company stow Group will invest $36 million to establish a 240,000 square foot production facility in Gordon County, Georgia, creating about 200 jobs. CEO Jos De Vuyst highlighted the strategic importance: “This new production facility will strengthen our presence in the U.S. and allow us to serve customers faster. It represents a major milestone for stow’s U.S. footprint”
Plant manager Michael Morgenroth said the state of the art plant will use advanced technologies and automation and provide “rewarding career opportunities for local residents”
Klauer Manufacturing Company, known for metal roofing accessories, opened a new 40,200 square foot facility in Tomball, Texas (including a 2,000 sq ft office) to produce residential roof flashing products. Initially serving as a warehouse, the site will begin manufacturing in early 2026. “Opening Klauer Texas allows us to bring our products closer to our customers and reinforce our commitment to service and innovation.”
Steel fabrication firm Merrill Steel will invest more than $32 million to establish its fourth manufacturing facility in Osceola, Arkansas. The 100,000 square foot plant will create 108 jobs and is scheduled to begin work in late 2025. President Fred Schwalbach said the addition “will perfectly complement our existing facilities, providing a high volume of quality fabricated and coated structural steel to our well established client base. We are overwhelmed by the support we are receiving from the state of Arkansas, the Osceola community and the local individuals associated with the steel industry” Arkansas Governor Sarah Sanders noted that the project reinforces Mississippi County’s status as a leading steel producing region.
Cronus Chemicals LLC announced a $2 billion investment to construct a new ammonia production facility in Tuscola, Illinois. Supported by the state’s EDGE incentive program, the plant will create 130 full time jobs and produce 950,000 short tons of nitrogen fertilizer annually.
“Our state-of-the-art facility in Tuscola represents a significant leap forward for the agriculture sector in Illinois and beyond. We extend our heartfelt thanks to Governor Pritzker and Team Illinois for their invaluable and continued support of our project,” said Chairman Melih Keyman.
GE Appliances (a Haier company) announced a $3 billion investment over five years to expand its U.S. manufacturing footprint across Kentucky, Alabama, Georgia, Tennessee and South Carolina. The plan will create 1,000 jobs and includes the construction of a new manufacturing facility in Camden, South Carolina, and expansions of existing plants in Selmer (Tennessee), LaFayette (Georgia), Decatur (Alabama) and Louisville (Kentucky).
“We are defining the future of manufacturing at GE Appliances by investing in our plants, people, and communities,” said Kevin Nolan, President and CEO of GE Appliances. said CEO Kevin Nolan.
JBS USA entered an agreement to purchase a 186,000 square foot facility in Ankeny, Iowa, where it will build its largest ready to eat bacon and sausage plant. The $100 million investment is expected to create 400 jobs. CEO Wesley Batista Filho explained that the expansion aligns with the company’s long term strategy: “Today’s announcement aligns with our long term strategy of offering more value added and prepared foods products to meet the needs of our customers and consumers. We are proud to grow our operations in Iowa, where we already operate four production facilities”
L3Harris Technologies completed a $100 million expansion of its satellite integration and test facility in Palm Bay, Florida, adding 94,000 square feet of manufacturing space to support the U.S. Space Force’s “Golden Dome” initiative. The expansion will produce next generation satellites and includes a 12,000 sq ft clean room. CEO Christopher E. Kubasik emphasized the company’s ability to meet evolving defense needs: “Accelerating the production of proven hardware for national missile warning and defense remains a priority as we align resources across the enterprise to support the President’s vision for America’s Golden Dome,” said CEO Christopher E. Kubasik.
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